申博体育平台

生命科学学院韩管助课题组在逆转录病毒进化和多样性研究取得重要进展

jinqi,jinhuashengwuxuezhuanyeqikanmolecular biology and evolution(yingxiangyinzi11.062)yi“a sister lineage of sampled retroviruses corroborates the complex evolution of retroviruses”weitizaixianfabiaoleshenbotiyupingtaixiaoshengmingkexuexueyuanhanguanzhujiaoshouketizuguanyunizhuanlubingdujinhuaheduoyangxingdezuixinyanjiujinzhan。

申博体育平台nizhuanlubingdukeguangfanganranjizhuidongwubingyinfaduozhongjibing(ruaizibing、aizhengdeng),duiquanqiugonggongweishengjiankanggouchengleyanzhongtiaozhan。nizhuanlubingdudefuzhixuyaojiangbingdurnanizhuanluchengshuangliandnabingzhenghedaosuzhujiyinzuzhong。nizhuanlubingduouerhuiganransuzhushengzhixibao,zhenghedenizhuanlubingdubianhuicongqindaichuandaozidai,xingchengneiyuanxingnizhuanlubingdu。neiyuanxingnizhuanlubingdujiluleguoqufashengdebingduganranshijian,weiyanjiunizhuanlubingdudeyuangujinhuayijisuzhuyunizhuanlubingdujiandejinhuajunbeijingsaitigonglezhongyaode“fenzihuashi”。jingguoyibaiduoniandeyanjiu,dayueyou70duozhongwaiyuanxingnizhuanlubingdubeifaxian。zheixiewaiyuanxingnizhuanlubingdukeyifenweilianggeyake,jizhengnizhuanlubingduyake(orthoretrovirinae)hepaomonizhuanlubingduyake(spumaretrovirinae)。qizhong,zhengnizhuanlubingduyakebaokuoliugeshu,erpaomonizhuanlubingduyakebaokuowugeshu。lingwai,guoquyanjiuhaizaijizhuidongwujiyinzuzhongfaxianleshuyiwanjideneiyuanxingnizhuanlubingdu。muqianyibanrenweinizhuanlubingduduoyangxingkuangjiayijibenwancheng。

hanguanzhujiaoshouketizutongguoxitongfashengjiyinzuxuedefangfazaijizhuidongwujiyinzuzhongfaxianleyileiquanxindenizhuanlubingdu,bingjiangqimingmingweiluojinizhuanlubingdu(lokiretrovirus)。luojinizhuanlubingdukeguangfanganranjizhuidongwu,ruqisaiman、fuqiyugang、fuqiyugang、liangqidongwuyijipaxingdongwu。luojinizhuanlubingdujuyoudianxingdenizhuanlubingdujiyinzutezheng,danyouyouqizishendeteshuxing。luojinizhuanlubingdubianmayigequanxindesmcdanbai,gaidanbaikejiehednabingzaidiaokongransetidongtaiguochengzhongfahuizhongyaodezuoyong。lingwai,luojinizhuanlubingdudebeimodanbaiyuyixiefuyidanlianrnabingdu(rufunianbingdukehefeiyanbingduyakebingdu)deronghedanbaizhijianyoumingxiandetongyuanxing,zheidapolenizhuanlubingduhefuyidanlianrnabingduzhijiandebianjie。

申博体育平台tongguoduinizhuanlumeijinxingxitongfashengfenxifaxian,luojinizhuanlubingdushiyizhinizhuanlubingdude“jiemeiqun”,gouchenglenizhuanlubingdudeyigexindeyake。luojinizhuanlubingdudefaxianweiyanjiunizhuanlubingdudeyuangujinhuatigongleyigeshifenzhongyaodejiedian。tongguoduinizhuanlubingduqitadanbaidejinyibufenxifaxian,nizhuanlubingduzaijinhuaguochengzhongduocitihuanzishendehesuanmei(rnase h)hezhenghemei(integrase),shuomingjiegouyuxipai(domain shuffling)suzaolenizhuanlubingdujiyinzudefuzaxing。zongshang,luojinizhuanlubingdudefaxianjidatuozhanleshenbotiyupingtaiduiyunizhuanlubingduduoyangxingderenshi,weilijienizhuanlubingdudeqiyuan、jinhuayijishengwuxuetigonglequanxindeshijiao。

申博体育平台xiangguanyanjiufabiaozaijinhuashengwuxuezhuanyeqikanmolecular biology and evolutionshang(wenzhanglianjie: ),boshiyanjiushengwangjianhuatongxueweidiyizuozhe,hanguanzhujiaoshouweitongxunzuozhe。xiangguanyanjiushoudaoguojiazirankexuejijin、jiangsushengyoushixuekeshenbotiyupingtaixiangmudengdezhichi。


luojinizhuanlubingdudesuzhufanwei、jiyinzujiegouyijijinhuashi

  • 更新时间

    申博体育平台2020nian11yue09ri 14:17

  • 阅读量

  • 供稿

    shengkeyuan

  • 打印

南京市仙林大学城文苑路1号,
邮编 210023
.cn

分享到

申博体育平台 - 欢迎您 GD真人-GD真人厅 GD真人-GD真人厅 GD真人-GD真人厅 DT电子官网-首页 GD真人-GD真人厅 亚博vip2-亚博vip2019